LONP1
lon peptidase 1, mitochondrial
Synonyms:
LON, LONP, LonHS, PIM1, PRSS15, hLON
Species:
Human LONP1 (9361), Mouse Lonp1 (74142), Rat Lonp1 (170916), domestic guinea pig Lonp1 (100717869), domestic cat LONP1 (101093417), chicken LONP1 (768942), Zebrafish lonp1 (563257), naked mole-rat Lonp1 (101710908), dog LONP1 (611425), sheep LONP1 (101109965)
UniProtKB ID:
Gene ID:
- Human(9361) Summary: This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
- Mouse(74142) lon peptidase 1, mitochondrial
- Rat(170916) lon peptidase 1, mitochondrial
- domestic guinea pig(100717869) lon peptidase 1, mitochondrial
- domestic cat(101093417) lon peptidase 1, mitochondrial
- chicken(768942) lon peptidase 1, mitochondrial
- Zebrafish(563257) lon peptidase 1, mitochondrial
- naked mole-rat(101710908) lon peptidase 1, mitochondrial
- dog(611425) lon peptidase 1, mitochondrial
- sheep(101109965) lon peptidase 1, mitochondrial
- cow(510796) lon peptidase 1, mitochondrial
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PRSS15 antibody produced in mouse, clone 3B2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-LONP1 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-LONP1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
western blot
Anti-LONP1 Antibody, clone 1I18, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot