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LOXL1

lysyl oxidase-like 1

Synonyms:
LOL, LOXL
Species:
UniProtKB ID:
Gene ID:
  • Human(4016) Summary: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
  • Mouse(16949) lysyl oxidase-like 1
  • Rat(315714) lysyl oxidase-like 1
  • dog(100686150) lysyl oxidase-like 1
  • domestic guinea pig(100720568) lysyl oxidase-like 1
  • domestic cat(101089616) lysyl oxidase-like 1
  • naked mole-rat(101710365) lysyl oxidase-like 1
  • chicken(426411) lysyl oxidase-like 1
  • sheep(101112424) lysyl oxidase-like 1
  • Zebrafish(560115) lysyl oxidase-like 1
  • cow(281903) lysyl oxidase-like 1
  • Horse(100051862) lysyl oxidase-like 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LOXL1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rat
Application
western blot
Anti-LOXL1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, mouse, pig, rat
Application
western blot
Anti-LOXL1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LOXL1,
Species
human
MISSION® esiRNA, targeting mouse Loxl1,
Species
mouse