LPIN3
lipin 3
Synonyms:
LIPN3L, SMP2, dJ450M14.2, dJ450M14.3, dJ620E11.2
Species:
Human LPIN3 (64900), Mouse Lpin3 (64899), Rat Lpin3 (362261), dog LPIN3 (485876), chicken LPIN3 (101751036), chicken LPIN3 (101669703), cow LPIN3 (521637), domestic cat LPIN3 (101096222), naked mole-rat Lpin3 (101722006), sheep LPIN3 (101106450) ...More
UniProtKB ID:
Gene ID:
- Human(64900) Summary: Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1, LPIN2, and LPIN3). Human LPIN1 gene has been mapped to 2p25.; linkages of fat mass and serum leptin levels to this same region have been noted. Human LPIN2 and LPIN3 mapped to chromosomes 18p11 and 20q11-q12, respectively. The mouse genes encoding Lpin1, Lpin2, and Lpin3 mapped to chromosome 12, 17, and 2, respectively. [provided by RefSeq, Jul 2008]
- Mouse(64899) lipin 3
- Rat(362261) lipin 3
- dog(485876) lipin 3
- chicken(101751036) lipin 3
- chicken(101669703) lipin 3
- cow(521637) lipin 3
- domestic cat(101096222) lipin 3
- naked mole-rat(101722006) lipin 3
- sheep(101106450) lipin 3
- Horse(100055753) lipin 3
- domestic guinea pig(100733777) lipin 3
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LPIN3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-LPIN3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-LPIN3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species