LRRC8A
leucine rich repeat containing 8 family, member A
Synonyms:
AGM5, LRRC8
Species:
Human LRRC8A (56262), Mouse Lrrc8a (241296), Rat Lrrc8a (311846), Zebrafish lrrc8a (327642), chicken LRRC8A (417201), domestic guinea pig Lrrc8a (100726291), naked mole-rat Lrrc8a (101716040), dog LRRC8A (491309), cow LRRC8A (505605), sheep LRRC8A (101117230) ...More
UniProtKB ID:
Gene ID:
- Human(56262) Summary: This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(241296) leucine rich repeat containing 8A
- Rat(311846) leucine rich repeat containing 8 family, member A
- Zebrafish(327642) leucine rich repeat containing 8 family, member A
- chicken(417201) leucine rich repeat containing 8 family, member A
- domestic guinea pig(100726291) leucine rich repeat containing 8 family, member A
- naked mole-rat(101716040) leucine rich repeat containing 8 family, member A
- dog(491309) leucine rich repeat containing 8 family, member A
- cow(505605) leucine rich repeat containing 8 family, member A
- sheep(101117230) leucine rich repeat containing 8 family, member A
- domestic cat(101082860) leucine rich repeat containing 8 family, member A
- Horse(100066843) leucine rich repeat containing 8 family, member A
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LRRC8A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Monoclonal Anti-LRRC8A antibody produced in mouse, clone 8H9, purified immunoglobulin,
Species Reactivity
human
Application
ELISA
western blot
western blot