MANF
mesencephalic astrocyte-derived neurotrophic factor
Synonyms:
ARMET, ARP
Species:
Human MANF (7873), Mouse Manf (74840), Rat Manf (315989), domestic guinea pig Manf (100719906), naked mole-rat Manf (101719750), Horse MANF (100052301), cow MANF (540432), dog MANF (608421), fruit fly Manf (41983), Zebrafish manf (767691) ...More
UniProtKB ID:
Gene ID:
- Human(7873) Summary: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related. [provided by RefSeq, Jun 2010]
- Mouse(74840) mesencephalic astrocyte-derived neurotrophic factor
- Rat(315989) mesencephalic astrocyte-derived neurotrophic factor
- domestic guinea pig(100719906) mesencephalic astrocyte-derived neurotrophic factor
- naked mole-rat(101719750) mesencephalic astrocyte-derived neurotrophic factor
- Horse(100052301) mesencephalic astrocyte-derived neurotrophic factor
- cow(540432) mesencephalic astrocyte-derived neurotrophic factor
- dog(608421) mesencephalic astrocyte-derived neurotrophic factor
- fruit fly(41983) Mesencephalic astrocyte-derived neurotrophic factor
- Zebrafish(767691) mesencephalic astrocyte-derived neurotrophic factor
- chicken(770664) mesencephalic astrocyte-derived neurotrophic factor
- sheep(101118227) mesencephalic astrocyte-derived neurotrophic factor
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MANF Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-MANF antibody produced in rabbit, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species