MCM8
minichromosome maintenance complex component 8
Synonyms:
C20orf154, dJ967N21.5
Species:
Human MCM8 (84515), Mouse Mcm8 (66634), Rat Mcm8 (296178), domestic cat MCM8 (101088566), Horse MCM8 (100065561), cow MCM8 (507507), domestic guinea pig Mcm8 (100734936), chicken MCM8 (421314), Domestic Rabbit MCM8 (100337967), dog MCM8 (477163) ...More
UniProtKB ID:
Gene ID:
- Human(84515) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(66634) minichromosome maintenance deficient 8 (S. cerevisiae)
- Rat(296178) minichromosome maintenance complex component 8
- domestic cat(101088566) minichromosome maintenance complex component 8
- Horse(100065561) minichromosome maintenance complex component 8
- cow(507507) minichromosome maintenance complex component 8
- domestic guinea pig(100734936) minichromosome maintenance complex component 8
- chicken(421314) minichromosome maintenance complex component 8
- Domestic Rabbit(100337967) minichromosome maintenance complex component 8
- dog(477163) minichromosome maintenance complex component 8
- Thale Cress(820123) minichromosome maintenance 8
- sheep(101116498) minichromosome maintenance complex component 8
- naked mole-rat(101719798) minichromosome maintenance complex component 8
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MCM8 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-MCM8 Antibody, clone 2D4, ,
Species Reactivity
human, mouse
Application
ChIP
electron microscopy
immunocytochemistry
immunoprecipitation (IP)
western blot
electron microscopy
immunocytochemistry
immunoprecipitation (IP)
western blot
Anti-MCM8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-MCM8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence