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MSL3

male-specific lethal 3 homolog (Drosophila)

Synonyms:
MSL3L1
Species:
UniProtKB ID:
Gene ID:
  • Human(10943) Summary: This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
  • Mouse(17692) male-specific lethal 3 homolog (Drosophila)
  • Rat(317464) male-specific lethal 3 homolog (Drosophila)
  • Horse(100054131) male-specific lethal 3 homolog (Drosophila)
  • dog(491742) male-specific lethal 3 homolog (Drosophila)
  • domestic cat(101086287) male-specific lethal 3 homolog (Drosophila)
  • chicken(418641) male-specific lethal 3 homolog (Drosophila)
  • Thale Cress(842187) MSCS-like 3
  • domestic guinea pig(100713886) male-specific lethal 3 homolog (Drosophila)
  • naked mole-rat(101698996) male-specific lethal 3 homolog (Drosophila)
  • sheep(101119018) male-specific lethal 3 homolog (Drosophila)
  • cow(515220) male-specific lethal 3 homolog (Drosophila)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MSL3L1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
Anti-MSL3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-MSL3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-MSL3-like 1 Antibody, from rabbit,
Species Reactivity
human
Application
ChIP
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Msl3,
Species
mouse
MISSION® esiRNA, targeting human MSL3,
Species
human