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NDRG1

N-myc downstream regulated 1

Synonyms:
CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5
Species:
UniProtKB ID:
Gene ID:
  • Human(10397) Summary: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(17988) N-myc downstream regulated gene 1
  • Rat(299923) N-myc downstream regulated 1
  • cow(504499) N-myc downstream regulated 1
  • naked mole-rat(101722001) N-myc downstream regulated 1
  • domestic guinea pig(100728790) N-myc downstream regulated 1
  • sheep(101120172) N-myc downstream regulated 1
  • domestic cat(101089078) N-myc downstream regulated 1
  • Horse(100068997) N-myc downstream regulated 1
  • dog(482049) N-myc downstream regulated 1
  • chicken(420321) N-myc downstream regulated 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NDRG1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, human
Application
western blot
Monoclonal Anti-NDRG1 antibody produced in mouse, clone 2D7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Phospho-NDRG1 (Thr346) Antibody, clone 5N4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

inhibition assay

western blot
Anti-NDRG1 Mouse mAb (2D7), liquid, clone 2D7, Calbiochem®,
Species Reactivity
human
Application
Anti-NDRG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ndrg1,
Species
mouse
MISSION® esiRNA, targeting human NDRG1,
Species
human