NEFL
neurofilament, light polypeptide
Synonyms:
CMT1F, CMT2E, NF-L, NF68, NFL
Species:
Human NEFL (4747), Mouse Nefl (18039), Rat Nefl (83613), chicken NEFL (419528), sheep NEFL (101119539), cow NEFL (281348), dog NEFL (477378), naked mole-rat Nefl (101704332), domestic cat NEFL (101081039), domestic guinea pig Nefl (100731797)
UniProtKB ID:
Gene ID:
- Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
- Mouse(18039) neurofilament, light polypeptide
- Rat(83613) neurofilament, light polypeptide
- chicken(419528) neurofilament, light polypeptide
- sheep(101119539) neurofilament, light polypeptide
- cow(281348) neurofilament, light polypeptide
- dog(477378) neurofilament, light polypeptide
- naked mole-rat(101704332) neurofilament, light polypeptide
- domestic cat(101081039) neurofilament, light polypeptide
- domestic guinea pig(100731797) neurofilament, light polypeptide
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Antibodies
Product Number
Description
Species Reactivity
Application
Neurofilament (2F11) Mouse Monoclonal Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Anti-NEFL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-phospho-NFL (Ser473) Antibody, clone 4F8, clone 4F8, from mouse,
Species Reactivity
bovine, human, mouse, porcine, rat, rhesus macaque
Application
immunohistochemistry
western blot
western blot
Neurofilament Antibodies Investigator Antibody Mini-Pack, anti-neurofilament H&M antibody, anti-neurofilament H antibody, and anti-neurofilament L antibody,
Species Reactivity
Application
Monoclonal Anti-NEFL antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL4729, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species