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NFKBIA

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Synonyms:
IKBA, MAD-3, NFKBI
Species:
UniProtKB ID:
Gene ID:
  • Human(4792) Summary: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
  • Mouse(18035) nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • Rat(25493) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • naked mole-rat(101709256) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic guinea pig(100723189) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic cat(101090622) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • sheep(780520) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • chicken(396093) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • dog(480291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • cow(282291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NFKBIA (Ab-42) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-phospho-IkappaB-α (pSer32/36) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-IkappaB-α (pTyr42) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
Anti-phospho-NFKBIA (pSer32/pSer36) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-NFKBIA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
I?Bα, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nfkbia,
Species
mouse
MISSION® esiRNA, targeting human NFKBIA,
Species
human