NLRP10
NLR family, pyrin domain containing 10
Synonyms:
CLR11.1, NALP10, NOD8, PAN5, PYNOD
Species:
Human NLRP10 (338322), Mouse Nlrp10 (244202), Rat Nlrp10 (293426), dog NLRP10 (611323), Horse NLRP10 (100070865), domestic cat NLRP10 (101089644), naked mole-rat Nlrp10 (101702326)
UniProtKB ID:
Gene ID:
- Human(338322) Summary: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(244202) NLR family, pyrin domain containing 10
- Rat(293426) NLR family, pyrin domain containing 10
- dog(611323) NLR family, pyrin domain containing 10
- Horse(100070865) NLR family, pyrin domain containing 10
- domestic cat(101089644) NLR family, pyrin domain containing 10
- naked mole-rat(101702326) NLR family, pyrin domain containing 10
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NLRP10 Antibody, clone 8H2, clone 8H2, from rat,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-NALP10 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-NLRP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NLRP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot