NLRP6
NLR family, pyrin domain containing 6
Synonyms:
AVR, CLR11.4, NALP6, NAVR, NAVR/AVR, PAN3, PYPAF5
Species:
Human NLRP6 (171389), Mouse Nlrp6 (101613), Rat Nlrp6 (171390), cow NLRP6 (505101), dog NLRP6 (483394), domestic cat NLRP6 (101087351), domestic guinea pig Nlrp6 (100713876), naked mole-rat Nlrp6 (101721850), sheep NLRP6 (101106640)
UniProtKB ID:
Gene ID:
- Human(171389) Summary: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
- Mouse(101613) NLR family, pyrin domain containing 6
- Rat(171390) NLR family, pyrin domain containing 6
- cow(505101) NLR family, pyrin domain containing 6
- dog(483394) NLR family, pyrin domain containing 6
- domestic cat(101087351) NLR family, pyrin domain containing 6
- domestic guinea pig(100713876) NLR family, pyrin domain containing 6
- naked mole-rat(101721850) NLR family, pyrin domain containing 6
- sheep(101106640) NLR family, pyrin domain containing 6
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NLRP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NALP6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-NLRP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NLRP6 (NALP6) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat, rhesus macaque
Application
immunohistochemistry
western blot
western blot
ANTI-MOUSE NLRP6 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
mouse
Application
western blot
esiRNA
Product Number
Description
Species