Skip to Content
MilliporeSigma

NOD2

nucleotide-binding oligomerization domain containing 2

Synonyms:
ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
Species:
UniProtKB ID:
Gene ID:
  • Human(64127) Summary: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(257632) nucleotide-binding oligomerization domain containing 2
  • Rat(291912) nucleotide-binding oligomerization domain containing 2
  • Domestic Rabbit(100356594) nucleotide-binding oligomerization domain containing 2
  • sheep(780465) nucleotide-binding oligomerization domain containing 2
  • cow(444867) nucleotide-binding oligomerization domain containing 2
  • dog(487286) nucleotide-binding oligomerization domain containing 2
  • domestic cat(101096863) nucleotide-binding oligomerization domain containing 2
  • naked mole-rat(101709371) nucleotide-binding oligomerization domain containing 2
  • domestic guinea pig(100727812) nucleotide-binding oligomerization domain containing 2
  • Zebrafish(777696) nucleotide-binding oligomerization domain containing 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NOD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NOD2 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-NOD2 Antibody, clone 2D9, clone 2D9, from mouse,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NOD2,
Species
human
MISSION® esiRNA, targeting mouse Nod2,
Species
mouse