Skip to Content
MilliporeSigma

OGDH

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

Synonyms:
AKGDH, E1k, OGDC
Species:
UniProtKB ID:
Gene ID:
  • Human(4967) Summary: This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
  • Mouse(18293) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • Rat(360975) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • domestic cat(101096048) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • cow(534599) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • sheep(101115360) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • Domestic Rabbit(100359048) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • domestic guinea pig(100724083) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • naked mole-rat(101716205) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • chicken(426429) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • dog(475499) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-OGDH antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, horse, human
Application
western blot
Anti-OGDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-OGDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human OGDH,
Species
human
MISSION® esiRNA, targeting human KIAA0825,
Species
human