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Merck

P2RY12

purinergic receptor P2Y, G-protein coupled, 12

同義詞:
ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999
物種:
Human P2RY12 (64805), Mouse P2ry12 (70839), Rat P2ry12 (64803), dog P2RY12 (442958), cow P2RY12 (408007), sheep P2RY12 (101117897), naked mole-rat P2ry12 (101701294), domestic cat P2RY12 (101094044), domestic guinea pig P2ry12 (100720551)
UniProtKB ID:
Q9H244, D3DNJ5, Q546J7
基因 ID:
  • Human(64805) Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • Mouse(70839) purinergic receptor P2Y, G-protein coupled 12
  • Rat(64803) purinergic receptor P2Y, G-protein coupled, 12
  • dog(442958) purinergic receptor P2Y, G-protein coupled, 12
  • cow(408007) purinergic receptor P2Y, G-protein coupled, 12
  • sheep(101117897) purinergic receptor P2Y, G-protein coupled, 12
  • naked mole-rat(101701294) purinergic receptor P2Y, G-protein coupled, 12
  • domestic cat(101094044) purinergic receptor P2Y, G-protein coupled, 12
  • domestic guinea pig(100720551) purinergic receptor P2Y, G-protein coupled, 12

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Small Molecule - Agonist

產品編號
描述
物種
U4125
尿苷 5′-（二磷酸三氢） 钠盐 来源于酿酒酵母, 95-100%,
物種
human

Small Molecule - Allosteric Modulator

產品編號
描述
物種
SML2482
替格瑞洛, ≥98% (HPLC),
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
PHR1431
硫酸氢氯吡格雷, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
1140430
硫酸氯吡格雷, United States Pharmacopeia (USP) Reference Standard,
物種
human
SML0004
(S)-(+)-Clopidogrel hydrogensulfate, ≥98% (HPLC),
物種
human
T6654
噻氯匹定 盐酸盐, analytical standard, for drug analysis,
物種
human
SML0331
Prasugrel, ≥98% (HPLC),
物種
human

Antibodies

產品編號
描述
物種活性
應用
HPA014518
抗-P2RY12 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunohistochemistry
HPA013796
抗-P2RY12 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunohistochemistry
P4871
抗-嘌呤能受体P2Y12 兔抗, affinity isolated antibody, lyophilized powder,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot