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P2RY2

purinergic receptor P2Y, G-protein coupled, 2

Synonyms:
HP2U, P2RU1, P2U, P2U1, P2UR, P2Y2, P2Y2R
Species:
UniProtKB ID:
Gene ID:
  • Human(5029) Summary: The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]
  • Mouse(18442) purinergic receptor P2Y, G-protein coupled 2
  • Rat(29597) purinergic receptor P2Y, G-protein coupled, 2
  • domestic guinea pig(100730145) purinergic receptor P2Y, G-protein coupled, 2
  • naked mole-rat(101720626) purinergic receptor P2Y, G-protein coupled, 2
  • domestic cat(101099323) purinergic receptor P2Y, G-protein coupled, 2
  • Horse(100065753) purinergic receptor P2Y, G-protein coupled, 2
  • cow(282638) purinergic receptor P2Y, G-protein coupled, 2
  • chicken(428108) purinergic receptor P2Y, G-protein coupled, 2
  • dog(485203) purinergic receptor P2Y, G-protein coupled, 2

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Small Molecule - Agonist

Product Number
Description
Species
Uridine 5′-triphosphate trisodium salt solution, HPLC purified, aqueous solution for RNA polymerase transcription,
Species
rat, human
Uridine 5′-triphosphate trisodium salt dihydrate, ≥80%,
Species
rat, human
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, 95-100%,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
NF 023 hydrate, ≥98% (HPLC), solid,
Species
human
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate, solid, ≥98% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-P2RY2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
P2Y2, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse P2ry2,
Species
mouse
MISSION® esiRNA, targeting human P2RY2,
Species
human