P2RY2
purinergic receptor P2Y, G-protein coupled, 2
HP2U, P2RU1, P2U, P2U1, P2UR, P2Y2, P2Y2R
Human P2RY2 (5029), Mouse P2ry2 (18442), Rat P2ry2 (29597), domestic guinea pig P2ry2 (100730145), naked mole-rat P2ry2 (101720626), domestic cat P2RY2 (101099323), Horse P2RY2 (100065753), cow P2RY2 (282638), chicken P2RY2 (428108), dog P2RY2 (485203)
- Human(5029) Summary: The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]
- Mouse(18442) purinergic receptor P2Y, G-protein coupled 2
- Rat(29597) purinergic receptor P2Y, G-protein coupled, 2
- domestic guinea pig(100730145) purinergic receptor P2Y, G-protein coupled, 2
- naked mole-rat(101720626) purinergic receptor P2Y, G-protein coupled, 2
- domestic cat(101099323) purinergic receptor P2Y, G-protein coupled, 2
- Horse(100065753) purinergic receptor P2Y, G-protein coupled, 2
- cow(282638) purinergic receptor P2Y, G-protein coupled, 2
- chicken(428108) purinergic receptor P2Y, G-protein coupled, 2
- dog(485203) purinergic receptor P2Y, G-protein coupled, 2
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Small Molecule - Agonist
Uridine 5′-triphosphate trisodium salt solution, HPLC purified, aqueous solution for RNA polymerase transcription,
rat, human
Small Molecule - Antagonist
Antibodies
Anti-P2RY2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
human
western blot