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PAFAH1B1

platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)

Synonyms:
LIS1, LIS2, MDCR, MDS, PAFAH
Species:
UniProtKB ID:
Gene ID:
  • Human(5048) Summary: This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]
  • Mouse(18472) platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
  • Rat(83572) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
  • naked mole-rat(101709906) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
  • chicken(374224) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
  • dog(480656) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
  • domestic cat(100135766) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
  • Horse(100072490) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
  • cow(282513) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
  • sheep(101119146) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
  • domestic guinea pig(100734716) platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PAFAH1B1, (N-terminal) antibody produced in mouse, clone 5A5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-LIS1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-PAFAH1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-PAFAH1B1 antibody produced in mouse, clone 2C12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-LIS1 Antibody, clone 9O6X3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PAFAH1B1,
Species
human
MISSION® esiRNA, targeting mouse Pafah1b1,
Species
mouse