PCGF2
polycomb group ring finger 2
Synonyms:
MEL-18, RNF110, ZNF144
Species:
Human PCGF2 (7703), Mouse Pcgf2 (22658), Rat Pcgf2 (287662), sheep PCGF2 (101120343), domestic cat PCGF2 (101087022), chicken PCGF2 (425919), naked mole-rat Pcgf2 (101721189), dog PCGF2 (491035), Horse PCGF2 (100055282), cow PCGF2 (505147)
UniProtKB ID:
Gene ID:
- Human(7703) Summary: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008]
- Mouse(22658) polycomb group ring finger 2
- Rat(287662) polycomb group ring finger 2
- sheep(101120343) polycomb group ring finger 2
- domestic cat(101087022) polycomb group ring finger 2
- chicken(425919) polycomb group ring finger 2
- naked mole-rat(101721189) polycomb group ring finger 2
- dog(491035) polycomb group ring finger 2
- Horse(100055282) polycomb group ring finger 2
- cow(505147) polycomb group ring finger 2
- domestic guinea pig(100719492) polycomb group ring finger 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MEL18/PCGF2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-PCGF2 antibody produced in mouse, clone 4D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-PCGF2 antibody produced in mouse, clone 4C10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
western blot
western blot
Anti-PCGF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-PCGF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence