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PHLPP1

PH domain and leucine rich repeat protein phosphatase 1

Synonyms:
PHLPP, PLEKHE1, SCOP
Species:
UniProtKB ID:
Gene ID:
  • Human(23239) Summary: This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
  • Mouse(98432) PH domain and leucine rich repeat protein phosphatase 1
  • Rat(59265) PH domain and leucine rich repeat protein phosphatase 1
  • Horse(100057142) PH domain and leucine rich repeat protein phosphatase 1
  • domestic guinea pig(100723560) PH domain and leucine rich repeat protein phosphatase 1
  • naked mole-rat(101701316) PH domain and leucine rich repeat protein phosphatase 1
  • cow(615982) PH domain and leucine rich repeat protein phosphatase 1
  • domestic cat(101091156) PH domain and leucine rich repeat protein phosphatase 1
  • dog(476179) PH domain and leucine rich repeat protein phosphatase 1
  • chicken(420904) PH domain and leucine rich repeat protein phosphatase 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PHLPP1 (N-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-PHLPP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-PHLPP1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse PHLPP1,
Species
mouse
MISSION® esiRNA, targeting human PHLPP1,
Species
human