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PLCG2

phospholipase C, gamma 2 (phosphatidylinositol-specific)

Synonyms:
APLAID, FCAS3
Species:
UniProtKB ID:
Gene ID:
  • Human(5336) Summary: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011]
  • Mouse(234779) phospholipase C, gamma 2
  • Rat(29337) phospholipase C, gamma 2
  • chicken(415805) phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • Zebrafish(561747) phospholipase C, gamma 2
  • cow(281988) phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • cow(100337091) phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • Horse(100055670) phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • domestic cat(101080675) phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • dog(489692) phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • sheep(101122126) phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • naked mole-rat(101715321) phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • domestic guinea pig(100726796) phospholipase C, gamma 2 (phosphatidylinositol-specific)

Custom & Knockdown Gene Products

  • siRNA

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  • shRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-PLCG2 (pTyr753) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
Anti-phospho-PLCG2 (pTyr1217) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
Anti-Phospho-PLCG2-Y1217 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-Phospho-PLCG2-Y759 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Anti-PLC gamma 2 (PLCG2) Antibody, clone 7I1C9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PLCG2,
Species
human
MISSION® esiRNA, targeting mouse Plcg2,
Species
mouse