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PPP1R1B

protein phosphatase 1, regulatory (inhibitor) subunit 1B

Synonyms:
DARPP-32, DARPP32
Species:
UniProtKB ID:
Gene ID:
  • Human(84152) Summary: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(19049) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • Rat(360616) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • cow(282459) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • domestic cat(101090972) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • dog(608394) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • sheep(101103077) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • Zebrafish(100884132) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • chicken(426639) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • naked mole-rat(101708486) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • domestic guinea pig(100726824) protein phosphatase 1, regulatory (inhibitor) subunit 1B

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DARPP-32, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-PPP1R1B antibody produced in mouse, clone 3G11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-PPP1R1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-PPP1R1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-phospho-DARPP-32 (pThr34) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
DARPP-32, recombinant, His-tagged, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ppp1r1b,
Species
mouse
MISSION® esiRNA, targeting human PPP1R1B,
Species
human