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PRDM16

PR domain containing 16

Synonyms:
CMD1LL, LVNC8, MEL1, PFM13
Species:
Human PRDM16 (63976), Mouse Prdm16 (70673), Rat Prdm16 (100366024), dog PRDM16 (479582), domestic cat PRDM16 (101090880), sheep PRDM16 (101120004), cow PRDM16 (100137803), Horse PRDM16 (100060844), Zebrafish prdm16 (559174), domestic guinea pig Prdm16 (100714489) ...More
UniProtKB ID:
Q9HAZ2, A6NHQ8, B1AJP7, B1AJP8, B1AJP9, B1WB48, Q8WYJ9, Q9C0I8
Gene ID:
  • Human(63976) Summary: The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(70673) PR domain containing 16
  • Rat(100366024) PR domain containing 16
  • dog(479582) PR domain containing 16
  • domestic cat(101090880) PR domain containing 16
  • sheep(101120004) PR domain containing 16
  • cow(100137803) PR domain containing 16
  • Horse(100060844) PR domain containing 16
  • Zebrafish(559174) PR domain containing 16
  • domestic guinea pig(100714489) PR domain containing 16
  • naked mole-rat(101721685) PR domain containing 16
  • chicken(419388) PR domain containing 16

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1300006
Anti-PRDM16 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
ABD130
Anti-PRDM16 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry
western blot
ABE543
Anti-PRDM16 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, canine, guinea pig, horse, human, nonhuman primates
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB2900806
Anti-PRDM16 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
HPA050343
Anti-PRDM16 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence