PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
Synonyms:
Species:
Human PRKAB2 (5565), Mouse Prkab2 (108097), Rat Prkab2 (64562), dog PRKAB2 (612807), cow PRKAB2 (512665), Horse PRKAB2 (100034095), naked mole-rat Prkab2 (101720100), domestic cat PRKAB2 (101092284), domestic guinea pig Prkab2 (100728100), Zebrafish prkab2 (100170795) ...More
UniProtKB ID:
Gene ID:
- Human(5565) Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
- Mouse(108097) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- Rat(64562) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- dog(612807) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- cow(512665) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- Horse(100034095) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- naked mole-rat(101720100) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- domestic cat(101092284) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- domestic guinea pig(100728100) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- Zebrafish(100170795) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- sheep(101113114) protein kinase, AMP-activated, beta 2 non-catalytic subunit
- chicken(427017) protein kinase, AMP-activated, beta 2 non-catalytic subunit
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PRKAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PRKAB2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-PRKAB2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species
AMPK (α2/β2/γ2), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
AMPK (α2/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
AMPK (α1/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human