Skip to Content
MilliporeSigma

PRKDC

protein kinase, DNA-activated, catalytic polypeptide

Synonyms:
DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350
Species:
UniProtKB ID:
Gene ID:
  • Human(5591) Summary: This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
  • Mouse(19090) protein kinase, DNA activated, catalytic polypeptide
  • Rat(360748) protein kinase, DNA activated, catalytic polypeptide
  • chicken(395376) protein kinase, DNA-activated, catalytic polypeptide
  • domestic cat(101088389) protein kinase, DNA-activated, catalytic polypeptide
  • domestic guinea pig(100724826) protein kinase, DNA-activated, catalytic polypeptide
  • cow(512740) protein kinase, DNA-activated, catalytic polypeptide
  • naked mole-rat(101722248) protein kinase, DNA-activated, catalytic polypeptide
  • sheep(101111377) protein kinase, DNA-activated, catalytic polypeptide
  • Domestic Rabbit(100125348) protein kinase, DNA-activated, catalytic polypeptide
  • dog(474176) protein kinase, DNA-activated, catalytic polypeptide

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PRKDC (Ab-2609) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-phospho-DNA-PK (pSer2056) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
ANTI-PHOSPHO-DNA-PK(T2609) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
Anti-DNA-PKcs Antibody, clone 3A9.1, clone 3A9.1, from mouse,
Species Reactivity
human
Application
western blot
Anti-Phospho-PRKDC-S2056 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
α-Naphthoflavone, ≥98%,
Species
human, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PRKDC,
Species
human
MISSION® esiRNA, targeting mouse Prkdc,
Species
mouse