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PTP4A3

protein tyrosine phosphatase type IVA, member 3

Synonyms:
PRL-3, PRL-R, PRL3
Species:
UniProtKB ID:
Gene ID:
  • Human(11156) Summary: The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq, Jul 2008]
  • Mouse(19245) protein tyrosine phosphatase 4a3
  • Rat(362930) protein tyrosine phosphatase type IVA, member 3
  • sheep(101120416) protein tyrosine phosphatase type IVA, member 3
  • domestic guinea pig(100724863) protein tyrosine phosphatase type IVA, member 3
  • domestic cat(101096639) protein tyrosine phosphatase type IVA, member 3
  • Zebrafish(406460) protein tyrosine phosphatase type IVA, member 3
  • chicken(768713) protein tyrosine phosphatase type IVA, member 3
  • naked mole-rat(101706683) protein tyrosine phosphatase type IVA, member 3
  • dog(606961) protein tyrosine phosphatase type IVA, member 3
  • cow(100137722) protein tyrosine phosphatase type IVA, member 3

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Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-PRL3 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-PRL-3 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Proteins

Product Number
Description
Species
PRL-3 (2-173) Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PTP4A3,
Species
human