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PTPRO

protein tyrosine phosphatase, receptor type, O

Synonyms:
GLEPP1, NPHS6, PTP-OC, PTP-U2, PTPROT, PTPU2, R-PTP-O
Species:
UniProtKB ID:
Gene ID:
  • Human(5800) Summary: This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]
  • Mouse(19277) protein tyrosine phosphatase, receptor type, O
  • Rat(50677) protein tyrosine phosphatase, receptor type, O
  • Zebrafish(407676) protein tyrosine phosphatase, receptor type, O
  • Horse(100064067) protein tyrosine phosphatase, receptor type, O
  • chicken(373911) protein tyrosine phosphatase, receptor type, O
  • domestic cat(101098147) protein tyrosine phosphatase, receptor type, O
  • dog(486664) protein tyrosine phosphatase, receptor type, O
  • cow(541043) protein tyrosine phosphatase, receptor type, O
  • naked mole-rat(101716353) protein tyrosine phosphatase, receptor type, O
  • domestic guinea pig(100714951) protein tyrosine phosphatase, receptor type, O

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PTPRO antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-PTPRO antibody produced in mouse, clone 3F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-GLEPP1/PTPRO Antibody, clone 5C11, clone 5C11, from mouse,
Species Reactivity
human
Application
electron microscopy
immunofluorescence

immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PTPRO,
Species
human