Skip to Content
MilliporeSigma

PVRL2

poliovirus receptor-related 2 (herpesvirus entry mediator B)

Synonyms:
CD112, HVEB, PRR2, PVRR2
Species:
UniProtKB ID:
Gene ID:
  • Human(5819) Summary: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(19294) poliovirus receptor-related 2
  • Rat(308417) poliovirus receptor-related 2
  • sheep(101111996) poliovirus receptor-related 2 (herpesvirus entry mediator B)
  • cow(505580) poliovirus receptor-related 2 (herpesvirus entry mediator B)
  • naked mole-rat(101715823) poliovirus receptor-related 2 (herpesvirus entry mediator B)
  • Horse(100065463) poliovirus receptor-related 2 (herpesvirus entry mediator B)
  • domestic guinea pig(100730603) poliovirus receptor-related 2 (herpesvirus entry mediator B)
  • dog(611060) poliovirus receptor-related 2 (herpesvirus entry mediator B)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PVRL2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-NECTIN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-Nectin-2/PVRL2 antibody produced in mouse, clone R2.5254.2, purified from hybridoma cell culture,
Species Reactivity
human, monkey, mouse, rat
Application
ELISA
flow cytometry

immunocytochemistry

western blot