RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
Synonyms:
CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1
Species:
Human RASGRF1 (5923), Mouse Rasgrf1 (19417), Rat Rasgrf1 (192213), Horse RASGRF1 (100050202), chicken RASGRF1 (415578), naked mole-rat Rasgrf1 (101699491), domestic cat RASGRF1 (101092941), cow RASGRF1 (520039), sheep RASGRF1 (101113014), domestic guinea pig Rasgrf1 (100731687)
UniProtKB ID:
Gene ID:
- Human(5923) Summary: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
- Mouse(19417) RAS protein-specific guanine nucleotide-releasing factor 1
- Rat(192213) RAS protein-specific guanine nucleotide-releasing factor 1
- Horse(100050202) Ras protein-specific guanine nucleotide-releasing factor 1
- chicken(415578) Ras protein-specific guanine nucleotide-releasing factor 1
- naked mole-rat(101699491) Ras protein-specific guanine nucleotide-releasing factor 1
- domestic cat(101092941) Ras protein-specific guanine nucleotide-releasing factor 1
- cow(520039) Ras protein-specific guanine nucleotide-releasing factor 1
- sheep(101113014) Ras protein-specific guanine nucleotide-releasing factor 1
- domestic guinea pig(100731687) Ras protein-specific guanine nucleotide-releasing factor 1
- dog(488774) Ras protein-specific guanine nucleotide-releasing factor 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RASGRF1 (S929) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-phospho-Ras-GRF1 (pSer916) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-RASGRF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Phospho-RASGRF1-S929 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
dot blot
dot blot