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MilliporeSigma

RCAN1

regulator of calcineurin 1

Synonyms:
ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Species:
UniProtKB ID:
Gene ID:
  • Human(1827) Summary: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(54720) regulator of calcineurin 1
  • Rat(266766) regulator of calcineurin 1
  • dog(607887) regulator of calcineurin 1
  • cow(539640) regulator of calcineurin 1
  • naked mole-rat(101705243) regulator of calcineurin 1
  • domestic cat(101085821) regulator of calcineurin 1
  • domestic guinea pig(100724800) regulator of calcineurin 1
  • chicken(418510) regulator of calcineurin 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RCAN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-Calcipressin-1, serum, from rabbit,
Species Reactivity
human, rat
Application
immunocytochemistry
western blot
Anti-RCAN1, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat, sheep
Application
western blot
Anti-RCAN1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
canine, human, mouse, rat
Application
western blot
Monoclonal Anti-DSCR1 antibody produced in mouse, clone 1G7, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Rcan1,
Species
mouse
MISSION® esiRNA, targeting human RCAN1,
Species
human