RPSA
ribosomal protein SA
Synonyms:
37LRP, 67LR, LAMBR, LAMR1, LBP, LBP/p40, LRP, LRP/LR, NEM/1CHD4, SA, lamR, p40
Species:
Human RPSA (3921), Mouse Rpsa (16785), Rat Rpsa (29236), Zebrafish rpsa (394027), chicken RPSA (395181), dog RPSA (477029), cow RPSA (281898), Horse RPSA (100055367), domestic cat RPSA (101098981), Domestic Rabbit RPSA (100144340) ...More
UniProtKB ID:
Gene ID:
- Human(3921) Summary: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(16785) ribosomal protein SA
- Rat(29236) ribosomal protein SA
- Zebrafish(394027) ribosomal protein SA
- chicken(395181) ribosomal protein SA
- dog(477029) ribosomal protein SA
- cow(281898) ribosomal protein SA
- Horse(100055367) ribosomal protein SA
- domestic cat(101098981) ribosomal protein SA
- Domestic Rabbit(100144340) ribosomal protein SA
- domestic guinea pig(100730948) ribosomal protein SA
- naked mole-rat(101697519) ribosomal protein SA
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-67kDa Laminin Receptor Antibody, clone 2Q8Q6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
western blot
Anti-Laminin Receptor Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
xenopus, bovine, human, mouse, porcine, rat, zebrafish
Application
immunocytochemistry
western blot
western blot