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SDHD

succinate dehydrogenase complex, subunit D, integral membrane protein

Synonyms:
CBT1, CII-4, CWS3, PGL, PGL1, QPs3, SDH4, cybS
Species:
UniProtKB ID:
Gene ID:
  • Human(6392) Summary: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]
  • Mouse(66925) succinate dehydrogenase complex, subunit D, integral membrane protein
  • Rat(363061) succinate dehydrogenase complex, subunit D, integral membrane protein
  • naked mole-rat(101702014) succinate dehydrogenase complex, subunit D, integral membrane protein
  • domestic guinea pig(100734731) succinate dehydrogenase complex, subunit D, integral membrane protein
  • chicken(419793) succinate dehydrogenase complex, subunit D, integral membrane protein
  • cow(281481) succinate dehydrogenase complex, subunit D, integral membrane protein
  • domestic cat(101095280) succinate dehydrogenase complex, subunit D, integral membrane protein
  • dog(479438) succinate dehydrogenase complex, subunit D, integral membrane protein
  • sheep(101111485) succinate dehydrogenase complex, subunit D, integral membrane protein
  • Goat(100860881) succinate dehydrogenase complex, subunit D, integral membrane protein

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SDHD antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-SDHD (CybS) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, human, mouse, rhesus macaque, sheep
Application
immunocytochemistry
western blot
Anti-SDHD Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
mouse
Application
immunocytochemistry
western blot
Anti-SDHD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-SDHD/CybS Antibody, clone 1F5-H2L2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, goat, human, monkey, mouse, sheep
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Sdhd,
Species
mouse
MISSION® esiRNA, targeting human SDHD,
Species
human