SFTPB
surfactant protein B
Synonyms:
PSP-B, SFTB3, SFTP3, SMDP1, SP-B
Species:
Human SFTPB (6439), Mouse Sftpb (20388), Rat Sftpb (192155), naked mole-rat Sftpb (101700017), domestic guinea pig Sftpb (100379548), dog SFTPB (100688334), Horse SFTPB (100034028), domestic cat SFTPB (101091359), sheep SFTPB (443043), cow SFTPB (507398)
UniProtKB ID:
Gene ID:
- Human(6439) Summary: This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]
- Mouse(20388) surfactant associated protein B
- Rat(192155) surfactant protein B
- naked mole-rat(101700017) surfactant protein B
- domestic guinea pig(100379548) surfactant associated protein B
- dog(100688334) surfactant protein B
- Horse(100034028) surfactant protein B
- domestic cat(101091359) surfactant protein B
- sheep(443043) surfactant protein B
- cow(507398) surfactant protein B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SFTPB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, human, rat
Application
immunohistochemistry
western blot
western blot
Anti-Surfactant Protein B Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-SFTPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-SFTPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-SFTPB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
esiRNA
Product Number
Description
Species