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SHMT2

serine hydroxymethyltransferase 2 (mitochondrial)

Synonyms:
GLYA, SHMT
Species:
UniProtKB ID:
Gene ID:
  • Human(6472) Summary: This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • Mouse(108037) serine hydroxymethyltransferase 2 (mitochondrial)
  • Rat(299857) serine hydroxymethyltransferase 2 (mitochondrial)
  • Zebrafish(100144628) serine hydroxymethyltransferase 2 (mitochondrial)
  • sheep(101101880) serine hydroxymethyltransferase 2 (mitochondrial)
  • domestic guinea pig(100725949) serine hydroxymethyltransferase 2 (mitochondrial)
  • Domestic Rabbit(100009293) serine hydroxymethyltransferase 2 (mitochondrial)
  • cow(507197) serine hydroxymethyltransferase 2 (mitochondrial)
  • Horse(100050119) serine hydroxymethyltransferase 2 (mitochondrial)
  • domestic cat(101091290) serine hydroxymethyltransferase 2 (mitochondrial)
  • dog(607458) serine hydroxymethyltransferase 2 (mitochondrial)
  • naked mole-rat(101721429) serine hydroxymethyltransferase 2 (mitochondrial)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SHMT2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-SHMT2 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-SHMT Antibody, clone 4D2.1, clone 4D2.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti- SHMT2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-SHMT2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SHMT2,
Species
human
MISSION® esiRNA, targeting mouse Shmt2,
Species
mouse