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SLC12A5

solute carrier family 12 (potassium/chloride transporter), member 5

Synonyms:
KCC2
Species:
UniProtKB ID:
Gene ID:
  • Human(57468) Summary: K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008]
  • Mouse(57138) solute carrier family 12, member 5
  • Rat(171373) solute carrier family 12 (potassium-chloride transporter), member 5
  • naked mole-rat(101716676) solute carrier family 12 (potassium/chloride transporter), member 5
  • domestic guinea pig(100721877) solute carrier family 12 (potassium/chloride transporter), member 5
  • chicken(777252) solute carrier family 12 (potassium/chloride transporter), member 5
  • dog(485905) solute carrier family 12 (potassium/chloride transporter), member 5
  • domestic cat(101085617) solute carrier family 12 (potassium/chloride transporter), member 5
  • cow(510157) solute carrier family 12 (potassium/chloride transporter), member 5
  • Horse(100071141) solute carrier family 12 (potassium/chloride transporter), member 5
  • sheep(101114128) solute carrier family 12 (potassium/chloride transporter), member 5

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-K+/Cl- Cotransporter (KCC2) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
canine, rat
Application
western blot
Monoclonal Anti-Kcc2 - Apc antibody produced in mouse, clone S1-12, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-Kcc2 antibody produced in mouse, clone S1-12, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-Kcc2 - PerCP antibody produced in mouse, clone S1-12, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-Kcc2 - Biotin antibody produced in mouse, clone S1-12, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SLC12A5,
Species
human
MISSION® esiRNA, targeting mouse Slc12a5,
Species
mouse