SLC26A5
solute carrier family 26 (anion exchanger), member 5
Synonyms:
DFNB61, PRES
Species:
Human SLC26A5 (375611), Mouse Slc26a5 (80979), Rat Slc26a5 (83819), dog SLC26A5 (483274), domestic cat SLC26A5 (100192303), Zebrafish slc26a5 (322846), chicken SLC26A5 (417715), domestic guinea pig Slc26a5 (100727496), naked mole-rat Slc26a5 (101720844), sheep SLC26A5 (101120234) ...More
UniProtKB ID:
Gene ID:
- Human(375611) Summary: This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
- Mouse(80979) solute carrier family 26, member 5
- Rat(83819) solute carrier family 26 (anion exchanger), member 5
- dog(483274) solute carrier family 26, member 5 (prestin)
- domestic cat(100192303) solute carrier family 26, member 5 (prestin)
- Zebrafish(322846) solute carrier family 26, member 5
- chicken(417715) solute carrier family 26, member 5 (prestin)
- domestic guinea pig(100727496) solute carrier family 26, member 5 (prestin)
- naked mole-rat(101720844) solute carrier family 26, member 5 (prestin)
- sheep(101120234) solute carrier family 26, member 5 (prestin)
- Domestic Rabbit(100216333) solute carrier family 26, member 5 (prestin)
- cow(536341) solute carrier family 26, member 5 (prestin)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SLC26A5 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-SLC26A5 antibody produced in mouse, clone 1F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-SLC26A5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry