SPTAN1
spectrin, alpha, non-erythrocytic 1
Synonyms:
EIEE5, NEAS, SPTA2
Species:
Human SPTAN1 (6709), Mouse Sptan1 (20740), Rat Sptan1 (64159), dog SPTAN1 (403484), domestic cat SPTAN1 (101080748), chicken SPTAN1 (374234), Horse SPTAN1 (100066945), sheep SPTAN1 (101107431), domestic guinea pig Sptan1 (100715698), Domestic Rabbit SPTAN1 (100350866) ...More
UniProtKB ID:
Gene ID:
- Human(6709) Summary: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
- Mouse(20740) spectrin alpha, non-erythrocytic 1
- Rat(64159) spectrin, alpha, non-erythrocytic 1
- dog(403484) spectrin, alpha, non-erythrocytic 1
- domestic cat(101080748) spectrin, alpha, non-erythrocytic 1
- chicken(374234) spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
- Horse(100066945) spectrin, alpha, non-erythrocytic 1
- sheep(101107431) spectrin, alpha, non-erythrocytic 1
- domestic guinea pig(100715698) spectrin, alpha, non-erythrocytic 1
- Domestic Rabbit(100350866) spectrin, alpha, non-erythrocytic 1
- cow(540108) spectrin, alpha, non-erythrocytic 1
- naked mole-rat(101701130) spectrin, alpha, non-erythrocytic 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Alpha Fodrin Antibody, clone 9H5V8, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-Fodrin Mouse mAb (Fod009), liquid, clone Fod009, Calbiochem®,
Species Reactivity
bovine, canine, human, mouse, porcine, rabbit, rat
Application
Anti-Spectrin α Antibody, clone 1D4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-SNTF (cleaved spectrin), serum, from rabbit,
Species Reactivity
bovine, human, mouse, porcine, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SPTAN1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
esiRNA
Product Number
Description
Species