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SUCLA2

succinate-CoA ligase, ADP-forming, beta subunit

Synonyms:
A-BETA, MTDPS5, SCS-betaA
Species:
UniProtKB ID:
Gene ID:
  • Human(8803) Summary: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008]
  • Mouse(20916) succinate-Coenzyme A ligase, ADP-forming, beta subunit
  • Rat(361071) succinate-CoA ligase, ADP-forming, beta subunit
  • Zebrafish(406299) succinate-CoA ligase, ADP-forming, beta subunit
  • domestic guinea pig(100714608) succinate-CoA ligase, ADP-forming, beta subunit
  • naked mole-rat(101706452) succinate-CoA ligase, ADP-forming, beta subunit
  • Domestic Rabbit(100356400) succinate-CoA ligase, ADP-forming, beta subunit
  • sheep(101113602) succinate-CoA ligase, ADP-forming, beta subunit
  • domestic cat(101096373) succinate-CoA ligase, ADP-forming, beta subunit
  • cow(511090) succinate-CoA ligase, ADP-forming, beta subunit
  • dog(485448) succinate-CoA ligase, ADP-forming, beta subunit
  • chicken(418857) succinate-CoA ligase, ADP-forming, beta subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SUCLA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-SUCLA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SUCLA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SUCLA2,
Species
human
MISSION® esiRNA, targeting human SUCLA2 (2),
Species
human
MISSION® esiRNA, targeting mouse Sucla2,
Species
mouse