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TADA3

transcriptional adaptor 3

Synonyms:
ADA3, NGG1, STAF54, TADA3L, hADA3
Species:
UniProtKB ID:
Gene ID:
  • Human(10474) Summary: DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
  • Mouse(101206) transcriptional adaptor 3
  • Rat(362414) transcriptional adaptor 3
  • Domestic Rabbit(100347359) transcriptional adaptor 3
  • cow(510184) transcriptional adaptor 3
  • sheep(101103513) transcriptional adaptor 3
  • Horse(100052239) transcriptional adaptor 3
  • dog(476541) transcriptional adaptor 3
  • chicken(416050) transcriptional adaptor 3
  • naked mole-rat(101698522) transcriptional adaptor 3
  • domestic guinea pig(100719194) transcriptional adaptor 3
  • domestic cat(101084429) transcriptional adaptor 3

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADA3 Antibody, clone 5C9/C8, clone 5C9/C8, from mouse,
Species Reactivity
human, mouse
Application
ChIP
immunocytochemistry

immunohistochemistry

western blot
Anti-TADA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TADA3,
Species
human