TARDBP
TAR DNA binding protein
Synonyms:
ALS10, TDP-43
Species:
Human TARDBP (23435), Mouse Tardbp (230908), Rat Tardbp (298648), sheep TARDBP (101114038), domestic guinea pig Tardbp (100718595), naked mole-rat Tardbp (101697585), Horse TARDBP (100051482), cow TARDBP (540632), dog TARDBP (478234), Zebrafish tardbp (325052) ...More
UniProtKB ID:
Gene ID:
- Human(23435) Summary: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
- Mouse(230908) TAR DNA binding protein
- Rat(298648) TAR DNA binding protein
- sheep(101114038) TAR DNA binding protein
- domestic guinea pig(100718595) TAR DNA binding protein
- naked mole-rat(101697585) TAR DNA binding protein
- Horse(100051482) TAR DNA binding protein
- cow(540632) TAR DNA binding protein
- dog(478234) TAR DNA binding protein
- Zebrafish(325052) TAR DNA binding protein
- chicken(419453) TAR DNA binding protein
- domestic cat(101097257) TAR DNA binding protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TDP-43/TARDB antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Phospho-TDP-43/TARDB-S409/S410 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-TDP-43 (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TARDBP (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-TDP-43 antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot