TGIF1
TGFB-induced factor homeobox 1
Synonyms:
HPE4, TGIF
Species:
Human TGIF1 (7050), Mouse Tgif1 (21815), Rat Tgif1 (316742), sheep TGIF1 (101105544), cow TGIF1 (510050), Zebrafish tgif1 (321756), domestic cat TGIF1 (101084747), dog TGIF1 (490537), domestic guinea pig Tgif1 (100716233), chicken TGIF1 (396339)
UniProtKB ID:
Gene ID:
- Human(7050) Summary: The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2013]
- Mouse(21815) TGFB-induced factor homeobox 1
- Rat(316742) TGFB-induced factor homeobox 1
- sheep(101105544) TGFB-induced factor homeobox 1
- cow(510050) TGFB-induced factor homeobox 1
- Zebrafish(321756) TGFB-induced factor homeobox 1
- domestic cat(101084747) TGFB-induced factor homeobox 1
- dog(490537) TGFB-induced factor homeobox 1
- domestic guinea pig(100716233) TGFB-induced factor homeobox 1
- chicken(396339) TGFB-induced factor homeobox 1
- naked mole-rat(101698504) TGFB-induced factor homeobox 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TGIF antibody produced in mouse, clone 1D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-TGIF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot