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TJP3

tight junction protein 3

Synonyms:
ZO-3, ZO3
Species:
UniProtKB ID:
Gene ID:
  • Human(27134) Summary: The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012]
  • Mouse(27375) tight junction protein 3
  • Rat(314640) tight junction protein 3
  • naked mole-rat(101702864) tight junction protein 3
  • dog(403852) tight junction protein 3
  • Zebrafish(373089) tight junction protein 3
  • chicken(420070) tight junction protein 3 (zona occludens 3)
  • domestic cat(101098036) tight junction protein 3
  • domestic guinea pig(100718150) tight junction protein 3
  • cow(407100) tight junction protein 3 (zona occludens 3)
  • Horse(100066918) tight junction protein 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TJP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-TJP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TJP3,
Species
human
MISSION® esiRNA, targeting mouse Tjp3,
Species
mouse