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TLR5

toll-like receptor 5

Synonyms:
SLEB1, TIL3
Species:
UniProtKB ID:
Gene ID:
  • Human(7100) Summary: This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
  • Mouse(53791) toll-like receptor 5
  • Rat(289337) toll-like receptor 5
  • naked mole-rat(101719481) toll-like receptor 5
  • cow(444870) toll-like receptor 5
  • sheep(554256) toll-like receptor 5
  • Goat(100860844) toll-like receptor 5
  • dog(488605) toll-like receptor 5
  • domestic cat(101082202) toll-like receptor 5
  • chicken(554217) toll-like receptor 5

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Mouse Tlr5 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
mouse
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-TLR5 antibody produced in mouse, clone 3E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-TLR5 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-TLR5 antibody produced in mouse, clone 4F7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-TLR5 Antibody, clone 6P1Q10, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Tlr5,
Species
mouse
MISSION® esiRNA, targeting human TLR5,
Species
human