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TREM2

triggering receptor expressed on myeloid cells 2

Synonyms:
TREM-2, Trem2a, Trem2b, Trem2c
Species:
UniProtKB ID:
Gene ID:
  • Human(54209) Summary: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
  • Mouse(83433) triggering receptor expressed on myeloid cells 2
  • Rat(301227) triggering receptor expressed on myeloid cells 2
  • sheep(101105447) triggering receptor expressed on myeloid cells 2
  • cow(506467) triggering receptor expressed on myeloid cells 2
  • domestic cat(101099297) triggering receptor expressed on myeloid cells 2
  • dog(608965) triggering receptor expressed on myeloid cells 2
  • chicken(419920) triggering receptor expressed on myeloid cells 2
  • naked mole-rat(101717064) triggering receptor expressed on myeloid cells 2
  • domestic guinea pig(100720722) triggering receptor expressed on myeloid cells 2

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ELISA

Product Number
Description
Species
Human TREM-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TREM2 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-TREM-2 Antibody, clone 1I11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
affinity binding assay
flow cytometry

immunocytochemistry

western blot
Anti-Trem2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
mouse
Application
ELISA
western blot
Anti-TREM-2 Antibody, clone 10H4.2, clone 10H4.2, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-TREM2, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Trem2,
Species
mouse
MISSION® esiRNA, targeting human TREM2,
Species
human