TRIM5
tripartite motif containing 5
RNF88, TRIM5alpha
Human TRIM5 (85363), Mouse Trim5 (667823), Rat Trim5 (308906), domestic cat TRIM5 (100302544), cow TRIM5 (505265), Domestic Rabbit TRIM5 (100126072)
- Human(85363) Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]
- Mouse(667823) tripartite motif-containing 5
- Rat(308906) tripartite motif-containing 5
- domestic cat(100302544) tripartite motif containing 5
- cow(505265) tripartite motif containing 5
- Domestic Rabbit(100126072) tripartite motif containing 5
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Antibodies
Anti-TRIM5/RNF88 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
human
ELISA
western blot
western blot
Anti-TRIM5 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
human
ELISA
immunohistochemistry
immunohistochemistry
Anti-TRIM5 alpha Antibody, from rabbit, purified by affinity chromatography,
human
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TRIM5 gamma antibody produced in rabbit, affinity isolated antibody,
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-TRIM5 antibody produced in mouse, clone 2A6, purified immunoglobulin, buffered aqueous solution,
human
ELISA