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TRIM5

tripartite motif containing 5

Synonyms:
RNF88, TRIM5alpha
Species:
UniProtKB ID:
Gene ID:
  • Human(85363) Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]
  • Mouse(667823) tripartite motif-containing 5
  • Rat(308906) tripartite motif-containing 5
  • domestic cat(100302544) tripartite motif containing 5
  • cow(505265) tripartite motif containing 5
  • Domestic Rabbit(100126072) tripartite motif containing 5

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TRIM5/RNF88 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-TRIM5 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
Anti-TRIM5 alpha Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-TRIM5 gamma antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-TRIM5 antibody produced in mouse, clone 2A6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TRIM5,
Species
human