UTRN
utrophin
Synonyms:
DMDL, DRP, DRP1
Species:
Human UTRN (7402), Mouse Utrn (22288), Rat Utrn (25600), chicken UTRN (421610), Zebrafish utrn (100034367), sheep UTRN (101120168), cow UTRN (534358), domestic cat UTRN (101096570), dog UTRN (442965), naked mole-rat Utrn (101717283)
UniProtKB ID:
Gene ID:
- Human(7402) Summary: This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
- Mouse(22288) utrophin
- Rat(25600) utrophin
- chicken(421610) utrophin
- Zebrafish(100034367) utrophin
- sheep(101120168) utrophin
- cow(534358) utrophin
- domestic cat(101096570) utrophin
- dog(442965) utrophin
- naked mole-rat(101717283) utrophin
- domestic guinea pig(100731640) utrophin
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Utrophin A, from rabbit,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-UTRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Utrophin Antibody, clone MANCHO3 (8A4), ,
Species Reactivity
canine, human, mouse
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot