WISP3
WNT1 inducible signaling pathway protein 3
Synonyms:
CCN6, LIBC, PPAC, PPD
Species:
Human WISP3 (8838), Mouse Wisp3 (327743), Rat Wisp3 (499461), domestic guinea pig Wisp3 (100727845), Horse WISP3 (100072430), cow WISP3 (784564), chicken WISP3 (770827), cow WISP3 (100849041), Zebrafish wisp3 (794092), domestic cat WISP3 (101086230) ...More
UniProtKB ID:
Gene ID:
- Human(8838) Summary: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(327743) WNT1 inducible signaling pathway protein 3
- Rat(499461) WNT1 inducible signaling pathway protein 3
- domestic guinea pig(100727845) WNT1 inducible signaling pathway protein 3
- Horse(100072430) WNT1 inducible signaling pathway protein 3
- cow(784564) WNT1 inducible signaling pathway protein 3
- chicken(770827) WNT1 inducible signaling pathway protein 3
- cow(100849041) WNT1 inducible signaling pathway protein 3
- Zebrafish(794092) WNT1 inducible signaling pathway protein 3
- domestic cat(101086230) WNT1 inducible signaling pathway protein 3
- naked mole-rat(101697161) WNT1 inducible signaling pathway protein 3
- dog(100686448) WNT1 inducible signaling pathway protein 3
- sheep(101109099) WNT1 inducible signaling pathway protein 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-WISP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-WISP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Proteins
Product Number
Description
Species
WISP-3 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human