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WWP1

WW domain containing E3 ubiquitin protein ligase 1

Synonyms:
AIP5, Tiul1, hSDRP1
Species:
UniProtKB ID:
Gene ID:
  • Human(11059) Summary: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008]
  • Mouse(107568) WW domain containing E3 ubiquitin protein ligase 1
  • Rat(297930) WW domain containing E3 ubiquitin protein ligase 1
  • dog(477930) WW domain containing E3 ubiquitin protein ligase 1
  • chicken(420212) WW domain containing E3 ubiquitin protein ligase 1
  • cow(513789) WW domain containing E3 ubiquitin protein ligase 1
  • Horse(100055725) WW domain containing E3 ubiquitin protein ligase 1
  • domestic cat(101095882) WW domain containing E3 ubiquitin protein ligase 1
  • naked mole-rat(101725489) WW domain containing E3 ubiquitin protein ligase 1
  • domestic guinea pig(100715948) WW domain containing E3 ubiquitin protein ligase 1
  • Domestic Rabbit(100350478) WW domain containing E3 ubiquitin protein ligase 1
  • sheep(101117426) WW domain containing E3 ubiquitin protein ligase 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-WWP1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-WWP1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, rabbit, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-WWP1 antibody produced in mouse, clone 1A7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-WWP1 antibody produced in mouse, clone 2B7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-WWP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Proteins

Product Number
Description
Species
WWP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥15% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Wwp1,
Species
mouse
MISSION® esiRNA, targeting mouse Wwp1,
Species
mouse
MISSION® esiRNA, targeting human WWP1,
Species
human