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特異性
Akt1/PKBα
免疫原
Peptide (C-RPHFPQFSYSASGTA) corresponding to the C-terminal (residues 466-480) of rat Akt1/PKBα
アプリケーション
Research Category
細胞シグナル伝達
細胞シグナル伝達
Research Sub Category
PI3K、Akt及びmTORシグナル伝達
PI3K、Akt及びmTORシグナル伝達
Detect Akt1/PKBα using this Anti-Akt1 Antibody, clone AW24 validated for use in IP & WB.
品質
routinely evaluated by immunoblot on RIPA lysates from human HEK293 cells
ターゲットの説明
~60kDa
物理的形状
Protein A purified
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
保管および安定性
2 years at -20°C
法的情報
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
05-796:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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A proposed mechanism underlying the effect of bacillus Calmette-Guérin (BCG) treatment for bladder cancer cells is as follows: BCG-induced crosslinking of cell-surface receptors results in the activation of signaling cascades, including cell-cycle regulators. However, the clinical significance of cell-cycle regulators
Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation.
Choi, JC; Muchir, A; Wu, W; Iwata, S; Homma, S; Morrow, JP; Worman, HJ
Science Translational Medicine null
Santhanalakshmi Sundaramurthy et al.
Neuropharmacology, 113(Pt A), 281-292 (2016-11-05)
Kappa opioid receptor (KOR) agonists produce dysphoria and psychotomimesis. While KOR agonists produce pro-depressant-like effects, KOR antagonists produce anti-depressant-like effects in rodent models. The cellular mechanisms and downstream effector(s) by which KOR ligands produce these effects are not clear. KOR
Chih-Jen Cheng et al.
Journal of the American Society of Nephrology : JASN, 22(3), 460-471 (2011-03-01)
WNK kinases stimulate endocytosis of ROMK channels to regulate renal K+ handling. Phosphatidylinositol 3-kinase (PI3K)-activating hormones, such as insulin and IGF 1, phosphorylate WNK1, but how this affects the regulation of ROMK abundance is unknown. Here, serum starvation of ROMK-transfected
Toshitaka Uehara et al.
Cytotechnology, 75(1), 49-62 (2023-01-31)
The standard treatment for non-muscle-invasive bladder cancer is intravesical Bacillus Calmette-Guérin (BCG) therapy, which is considered the only intravesical therapy that reduces the risk of progression to muscle-invasive cancer. BCG unresponsiveness, in which intravesical BCG therapy is ineffective, has become
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