420123-M

JNK Inhibitor II, Negative Control

The JNK Inhibitor II, Negative Control, also referenced under CAS 54642-23-8, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 別名: JNK Inhibitor II, Negative Control, N¹-Methyl-1,9-pyrazoloanthrone
• 実験式（ヒル表記法）: C₁₅H₁₀N₂O
• CAS番号: 54642-23-8
• 分子量: 234.25
• UNSPSCコード: 12352200

特性

• 品質水準: 100
• アッセイ: ≥97% (HPLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: yellow
• 溶解性: DMSO: 10 mg/mL
• 保管温度: −20°C

詳細

詳細

A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC₅₀ = 18 µM and 24 µM, respectively) compared to SP600125 (IC₅₀ = 40 nM and 90 nM, respectively).

A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC₅₀ = 18 µM and 24 µM, respectively) compared to SP600125 (IC₅₀ = 40 nM and 90 nM, respectively).

生物化学的／生理学的作用

Primary Target
A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119)

Target IC₅₀: 18 µM and 24 µM against JNK2 and JNK3, respectively

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.

その他情報

Shin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta1589, 311.
Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA98, 13681.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable