ABF203

Anti-S1P1 Antibody

from rabbit, purified by affinity chromatography

• 別名: Sphingosine-1-phosphate receptor 1, S1PR1, EDG1, ECGF1, S1P1, Endothelial differentiation G-protein coupled receptor 1, Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1, CD363
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• クローン: polyclonal
• application: IHC; WB
• 化学種の反応性: mouse
• テクニック: immunohistochemistry: suitable; western blot: suitable

特性

• 由来生物: rabbit
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: mouse
• 化学種の反応性（ホモロジーによる予測）: human (immunogen homology)
• テクニック: immunohistochemistry: suitable; western blot: suitable
• UniProtアクセッション番号: P21453
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... S1PR1(1901)

詳細

詳細

Sphingosine-1-phosphate receptor 1 (S1PR1, S1P1), also known as Endothelial differentiation G-protein coupled receptor 1 (EDG1, ECGF1), Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1, is a bioactive lysophospholipid that evokes diverse physiological effect on most types of cells and tissues. Recent studies suggest that S1P1 promotes lymph node egression by overcoming retention signals mediated by CCR7 and G alpha i-protein-coupled receptor signaling. S1P1 may be involved in the processes that regulate the differentiation of endothelial cells. S1P1 is expressed highly in endothelial cells, and to a lesser extent in vascular smooth muscle cells, fibroblasts, melanocytes and cells of epithelioid origin.

免疫原

KLH-conjugated linear peptide corresponding to human S1P1.

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
免疫シグナル伝達

Detect S1P1 using this rabbit polyclonal antibody, Anti-S1P1 Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected S1P1 in mouse thymus tissue.

品質

Evaluated by Western Blotting in mouse thymus tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected S1P1 in 15 µg of mouse thymus tissue lysate.

ターゲットの説明

~42 kDa observed. Uncharacterized bands may appear in some lysate(s).

物理的形状

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Mouse thymus tissue lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable